Our MoveKit™ BA Service provides comprehensive bile acid analysis using LC-MS with Orbitrap HRMS detection. This service delivers high-quality quantitative bile acid profiling across conjugated and unconjugated species and their sulfate derivatives.
Service Features
- Comprehensive Coverage: Analysis of 32 bile acid species including conjugated, unconjugated, and sulfated forms. Another 151 semi-quantitative targets including microbial conjugated bile acids (MCBA’s), murine bile acids, and free fatty acids.
- Matrix Compatibility: Validated on plasma, serum, urine, feces, and several tissues. Novel matrix validation is available.
- High Sensitivity: Extraction and MS analysis optimized for bile acid detection down to ~1nM.
- Quantitative Results: 32 stable-isotope labeled internal standards and reference-material based calibrators give the highest level of quantitative confidence.
- Detailed Reports: Comprehensive analytical reports with quality metrics.
What You Receive
- Quantification of bile acid species detected in your samples
- Transparent reporting using the MoveApp
- Expert consultation and support
- Publication-quality data and reporting
- Raw data upon request
Bile Acid Classes Covered
- Conjugated Bile Acids: Glycine and taurine conjugates
- Unconjugated Bile Acids: Primary and secondary bile acids
- Conjugated Bile Acid Sulfates: Sulfated conjugated forms
- Unconjugated Bile Acid Sulfates: Sulfated unconjugated forms
- Additional BA Conjugates: High-resolution analysis with MS/MS allows optional searching for lower abundance conjugated bile acid forms (additional charge)
Ideal For
- Liver, metabolic disease, gut/brain axis, and other translational medicine research
- Microbiome-host interaction studies